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Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition 3rd Edition, Kindle Edition

4.7 4.7 out of 5 stars 57 ratings

GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS

Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others.

The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations.

FEATURES

  • NEW chapter on neuroinflammation
  • All chemical structure illustrations have been redrawn and improved
  • Fully updated to reflect the latest breakthroughs and new drugs
  • The most well-written and easily understood work on the subject
  • More than 300 full-color illustrations!

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Editorial Reviews

From the Publisher

Eric J. Nestler, MD, PhD (New York, NY) Nash Family Professor of Neuroscience; Chairman, Department of Neuroscience and Director of the Mount Sinai Brain Institute, Mount Sinai School of Medicine.
Steven E. Hyman, MD (Cambridge, MA) Director, Stanley Center for Psychiatric Research, Broad Institute; Distinguished Service Professor of Stem Cell and Regenerative Biology Harvard University.
Robert C. Malenka, MD, PhD (Palo Alto, CA) Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences; Director, Nancy Friend Pritzker Laboratory, Stanford University School of Medicine.
David M. Holtzman, MD (St. Louis, MO) Andrew B. and Gretchen P. Jones Professor of Neurology Charlotte and Paul Hagemann Professor of Neurology Chairman, Department of Neurology Professor, Molecular Biology and Pharmacology Washington University School of Medicine in St. Louis Neurologist-in-Chief, Barnes-Jewish Hospital

About the Author

Eric J. Nestler, MD, PhD (New York, NY) Nash Family Professor of Neuroscience; Chairman, Department of Neuroscience and Director of the Mount Sinai Brain Institute, Mount Sinai School of Medicine.
Steven E. Hyman, MD (Cambridge, MA) Director, Stanley Center for Psychiatric Research, Broad Institute; Distinguished Service Professor of Stem Cell and Regenerative Biology Harvard University.
Robert C. Malenka, MD, PhD (Palo Alto, CA) Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences; Director, Nancy Friend Pritzker Laboratory, Stanford University School of Medicine.
David M. Holtzman, MD (St. Louis, MO) Andrew B. and Gretchen P. Jones Professor of Neurology Charlotte and Paul Hagemann Professor of Neurology Chairman, Department of Neurology Professor, Molecular Biology and Pharmacology Washington University School of Medicine in St. Louis Neurologist-in-Chief, Barnes-Jewish Hospital



Steven E. Hyman, MD is Provost of Harvard University and Professor of Neurobiology at Harvard Medical School, Boston, MA. From 1996 to 2001, he served as Director of the National Institute of Mental Health (NIMH), the component of the US National Institutes of Health charged with generating the knowledge needed to understand and treat mental illness. Before serving as Director of NIMH, Dr. Hyman was Professor of Psychiatry at Harvard Medical School, Director of Psychiatry Research at Massachusetts General Hospital , and the first faculty Director of Harvard University's Mind, Brain, and Behavior Initiative. In the laboratory he studied the molecular biology of neurotransmitter action. Dr. Hyman is a member of the Institute of Medicine of the National Academy of Sciences and of the American Academy of Arts and Sciences. He is currently serves as Editor of the Annual Review of Neuroscience. He received his BA from Yale College in 1974 summa cum laude, and his MA from the University of Cambridge in 1976, which he attended as a Mellon fellow studying the history and philosophy of science. He earned his MD from Harvard Medical School in 1980.

Robert C. Malenka, MD, PhD is Pritzker Professor of Psychiatry & Behavioral Sciences at Stanford University, Palo Alto, CA. He is a fellow of the American Academy of Arts and Sciences, a member of the Institute of Medicine of the National Academies and an Associate of the Neurosciences Research Program. He has won several awards including the International Prize in Neuroscience, the Distinguished Alumni Award from Stanford University and the Daniel Efron Award from the American College of Neuropsychopharmacology. A major goal of his laboratory is to elucidate both the specific molecular events that are responsible for the triggering of these various forms of synaptic plasticity and the exact modifications in synaptic proteins that are responsible for the observed, long-lasting changes in synaptic efficacy.

Product details

  • ASIN ‏ : ‎ B00P1JSO08
  • Publisher ‏ : ‎ McGraw Hill / Medical; 3rd edition (March 22, 2015)
  • Publication date ‏ : ‎ March 22, 2015
  • Language ‏ : ‎ English
  • File size ‏ : ‎ 69305 KB
  • Text-to-Speech ‏ : ‎ Enabled
  • Screen Reader ‏ : ‎ Supported
  • Enhanced typesetting ‏ : ‎ Enabled
  • X-Ray ‏ : ‎ Not Enabled
  • Word Wise ‏ : ‎ Not Enabled
  • Sticky notes ‏ : ‎ On Kindle Scribe
  • Print length ‏ : ‎ 1424 pages
  • Customer Reviews:
    4.7 4.7 out of 5 stars 57 ratings

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Customer reviews

4.7 out of 5 stars
4.7 out of 5
57 global ratings

Top reviews from the United States

Reviewed in the United States on September 26, 2018
This text book provides the underpinning in Neuropharmacology. If you do not have a strong backdrop in the field this text book will be helpful. In addition, it presents the information in an unequivocal way; easlily understood.
The first few chapters are introduction in molecular neurobiology (what are neurons, glis, synapse, etc), the signaling pathways, gene expression following neuronal activity, so on.
Then it dictates a chapter for each neurotransmitter.
The last section is for neurlogical disease (application of what is explained in the first two sections).
This textbook was my reference while taking the comprehensive exam for the graduate school.
One person found this helpful
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Reviewed in the United States on August 22, 2016
I bought this book not for a course or exam, but to answer some specific questions. As a clinical physician I thought it would be a reference text only. Now I find I can't put it down and have started to read it all the way through. Although dense with information in nearly every sentence, the book reads easily, explains concepts well, and is worth every penny twice over. I highly recommend this to anyone in medicine or pharmacology. I only wish it was available when I was a student.
13 people found this helpful
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Reviewed in the United States on March 5, 2020
Tbh this is the only textbook i’ve ever actually enjoyed reading. It is a paperback so you may want to cover it if you plan on carrying it around everywhere, the front cover of mine has bent in several places from going in and out of my backpack.
Reviewed in the United States on July 13, 2016
One of the best textbooks I own. I usually rent texts for courses and send them back at the end of semesters, but this is one I'm happy to have bought. An excellent introduction to the building blocks of the brain and their clinical significance.
5 people found this helpful
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Reviewed in the United States on June 8, 2019
An excellent background and foundation for neuropharmacologist. It is a powerful blend of Netter,Stahl,Goodman and Gilman.
One person found this helpful
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Reviewed in the United States on September 19, 2017
Excellent book. If you are in a professional program (med school, grad school for biomedical sciences, etc.) this book is an awesome resource.
Reviewed in the United States on November 13, 2018
Excellent coverage on a difficult subject by one of the best in the field.
Reviewed in the United States on November 25, 2019
Great reference book wonderful read great illustration

Top reviews from other countries

Translate all reviews to English
Diego Romero Pérez
4.0 out of 5 stars Buen tratado para comprender la plasticidad neuronal
Reviewed in Mexico on December 10, 2017
Buen libro para comprender mejor el funcionamiento del sistema nervioso y su influencia en el resto del organismo, explica la forma de transmisión de señales y su traducción en efectos concretos en sistemas y órganos.
Amazon Customer
5.0 out of 5 stars Five Stars
Reviewed in Canada on April 13, 2017
excellent
Cliente Amazon
4.0 out of 5 stars A must for neuroscientists
Reviewed in Spain on February 15, 2017
A comprehensive and visually attractive guide to the pharmacology of the nervous system. This particular edition is a bit flimsy, and must be handled with care. A part form that, is a must for neuroscientists.
Nimmerland
5.0 out of 5 stars Great intro
Reviewed in the United Kingdom on January 22, 2017
An excellent introduction, that manages to avoid being shallow. Great textbook or as further reading.
Atheistization
5.0 out of 5 stars One of the best books on neuropharmacology
Reviewed in the United Kingdom on September 24, 2014
Highly recommend it!
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