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The Switch: Ignite Your Metabolism with Intermittent Fasting, Protein Cycling, and Keto Hardcover – December 31, 2019

4.2 4.2 out of 5 stars 373 ratings
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How can you lose dramatic weight, ease chronic conditions, and stay healthier longer? Flip the switch on your metabolism with intermittent fasting, protein cycling, and keto!

Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life.

So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating?

Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, The Switch decodes the science of autophagy and teaches you how to control it and maximize its profound impact.
Previous page
  1. Print length
    320 pages
  2. Language
    English
  3. Publisher
    Gallery Books
  4. Publication date
    December 31, 2019
  5. Dimensions
    6 x 1.2 x 9 inches
  6. ISBN-10
    1982115394
  7. ISBN-13
    978-1982115395
  8. See all details
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From the Publisher

Editorial Reviews

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"I was blown away by this book. Through many years of research and an immersion in cutting-edge research, James Clement has produced the best book I’ve read on fasting and autophagy. Definitely worth the read!"
—David A. Sinclair, PhD, New York Times bestselling author of Lifespan

"The Switch will undoubtedly rewrite your health destiny."
—David Perlmutter, MD, #1 New York Times bestsellinga uthor of Grain Brain and Brain Wash

"James Clement is a rare trailblazer in scientific circles. The Switch offers a paradigm shift in the way we think about health—and how to avoid decline and illness. This is a must read."
—Mark Hyman, #1 New York Times bestselling author of Food: What the Heck Should I Cook?

"There is an easy way to make your cells stronger and younger. James Clement has done the science to crack the code for all of us to stay younger longer. Read this book!"
—Dave Asprey, founder of Bulletproof and New York Times bestselling author of The Bulletproof Diet

"The Switch is a sweeping and fascinating journey on the science of aging and life-extension. Additionally, Clement offers years of distilled research with a practical guide to switch on the body’s innate ability to rejuvenate itself to live a longer and healthier life."
—Travis Christofferson, author of Tripping Over the Truth and Curable

"The Switch is a breakthrough twenty-first-century antiaging book!"
—Durk Pearson, Scientist and Coauthor of the #1 national bestseller Life Extension

"A must-read for anybody interested in promoting lifespan and health span."
—Dr. Steve Horvath, Professor of Human Genetics & Biostatistics at UCLA

“The Switch is a very balanced book, with plenty of nuanced suggestions for how you can make your food situation just a little bit better without making too many radical changes.”—Mashable

About the Author

James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the past two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School. Through worldwide collaborations and in his own laboratory in Gainesville, Florida, he focuses on advancing cutting-edge biomedical discoveries so that humanity can take advantage of these antiaging breakthroughs. Visit him at JamesWClement.com or follow him on Twitter @JamesWClement.

Kristin Loberg has collaborated on a lengthy list of New York Times bestselling books, including Dr. David Perlmutter’s Grain Brain and Dr. David B. Agus’s The End of Illness and A Short Guide to a Long Life.

Product details

  • Publisher ‏ : ‎ Gallery Books; 1st edition (December 31, 2019)
  • Language ‏ : ‎ English
  • Hardcover ‏ : ‎ 320 pages
  • ISBN-10 ‏ : ‎ 1982115394
  • ISBN-13 ‏ : ‎ 978-1982115395
  • Item Weight ‏ : ‎ 1.04 pounds
  • Dimensions ‏ : ‎ 6 x 1.2 x 9 inches
  • Customer Reviews:
    4.2 4.2 out of 5 stars 373 ratings

About the author

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Mr. James W. Clement

Mr. James W. Clement

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Full content visible, double tap to read brief content.

James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the past two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School. Through worldwide collaborations and in his own laboratory in Gainesville, Florida, he focuses on advancing cutting-edge biomedical discoveries so that humanity can take advantage of these antiaging breakthroughs. Visit him at JamesWClement.com or follow him on Twitter @JamesWClement and Instagram @JWClement

Customer reviews

4.2 out of 5 stars
4.2 out of 5
373 global ratings

Top reviews from the United States

A Reader
5.0 out of 5 stars Very Helpful Book
Reviewed in the United States on February 6, 2020
Verified Purchase
I've read lots of books on health and diet. The Switch by James W. Clement has been the most helpful for me. I really appreciate the information that he shares. I think I've been following quite closely his outline, even before reading the book; I was doing intermittent fasting, and it works for me. I tried carnivore, and it was not quite what I needed. I don't have autoimmune issues like some do. I like his list of "Unlimited Foods", I have to watch the oxalates, so the smaller portions list works for me. I do think macadamia nuts are way overpriced, and other nuts will work for me; I like his list of oils. I have been eating more fish, mostly wild salmon. I really feel good eating salmon and not so much beef. Wild caught salmon is expensive, but by cutting out a lot of other foods and supplements I was taking, I can do it. I appreciate his list of supplements. When I was eating KETO, my total cholesterol shot up to over 300. I have to watch my blood pressure, and I think it's important for me to keep my cholesterol down somewhat. I have always exercised a lot, and I like that he encourages exercise. I'm 80 years old, and I want to have the best health I can have as long as I can. I really want to thank James Clement for writing this book and sharing what he has learned about health and diet. All of his information is so appreciated. Thank you!
36 people found this helpful
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Jim Gibbons
5.0 out of 5 stars Expert Advice on living a long and healthy life
Reviewed in the United States on January 3, 2020
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A very informative and easy read. I highly recommend this book.

Some great insights into slowing aging and leading a healthy life. Midway into my 60s, I am definitely feeling the passage of time and an aging body.

I definitely think radical life extension for those who want it is not too far away in the future. I think Clement's understanding about our body and maximizing health are second to none.

Seeing the names of the folks who have reviewed and endorsed this book has also impressed the heck out of me: George Church, David Sinclair, David Perlmutter, Dave Asprey, Durk Pearson, Steve Horvath, and many others.

I definitely plan on sending copies to friends and family members.
16 people found this helpful
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Moriarty
4.0 out of 5 stars Good information
Reviewed in the United States on June 4, 2020
Verified Purchase
Much of what is in this book can be found through a variety of sources, but this saves time by avoiding that research. It also is a book I refer back to for some things. The reason for the 4 stars is in some cases, the author yammers on and on, while I am looking for concrete information that I can apply, with concise background. The book could have been somewhat shorter and still be worth the price.

I have adopted some of his recommendations and noticed certain improvements, but the proof will be when I get tested, which haven't done yet due to this stupid virus shutdown.
3 people found this helpful
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JordanSparks
3.0 out of 5 stars Don't follow his advice
Reviewed in the United States on October 26, 2023
Verified Purchase
That's not how science works. The thousands of science papers he ingested don't support his conclusions. It's interesting to read about the mechanisms, but animal studies do NOT directly translate to human. The only way to know if a particular diet will work is to do the study in humans. Until then, it's really more accurate to say that we just don't know, and that's ok. Also, science works by the entire scientific community gradually coming to consensus on each issue. I guarantee that the current consensus is not to go on a ketogenic diet. If it was, then my doctor would be advising me to do so. If there were proven health benefits, then all doctors would clearly be recommending ketogenic diets. I know James means well, but he's a true outlier and you should firmly reject his advice. For example, if you follow his advice, you will most likely lose muscle mass and fall into disability sooner from sarcopenia.
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D. Pearson
5.0 out of 5 stars The Switch: A 21st Century DIY book on life extension, anti-sging, and rejuvination
Reviewed in the United States on January 4, 2020
Verified Purchase
This book is so good that my partner and I bought three copies; one for each of us, and a third for a physician friend.

Your cells have a master switch controlling growth and repair versus damage removal. To make new repairs you must remove old damage. Years of buildup of un-repaired damage can promote cardiovascular disease, Alzheimer’s, adult onset diabetes, and aging itself. “The Switch” tells you how you can flip your switch to slow and even partially reverse your aging. These do it yourself anti-aging methods are simple, safe, inexpensive, scientifically sound, and include 23 pages of scientific literature citations.
“The Switch” is a breakthrough 21st century anti-aging book!
Durk Pearson (MIT 1965), scientist and co-author of the #1 million copy best seller, “Life Extension, A Practical Scientific Approach”

"MURDER AT THE DUMP: THE CASE OF THE DEADLY LEFT-OVERS" Hmmm. The real title of this book is "THE SWITCH”, which explains two important processes that affect aging, one that promotes growth and largely speeds aging, while the other promotes waste removal, which is necessary for repair, and slows aging. With extensive documentation, the book shows how you can help decide which process is predominant at what time. This is the practical scientific approach for taking advantage of the switch.
Live Long & Prosper,
Sandy Shaw, B.S. Chemistry (UCLA, 1965) co-author, "Life Extension, a Practical Scientific Approach”
30 people found this helpful
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Robert T. Healey Sr.
5.0 out of 5 stars Fascinating book on living a healthy lifestyle & extending life span
Reviewed in the United States on January 10, 2020
Verified Purchase
I recently purchased a book entitled “The Switch” by a James Clement, a self-made brilliant microbiologist. I rate this book 5 stars. As some of us know, we have 30-40 trillion cells in our body. What was fascinating to me was the author tells that in each of our cells we have an ancient mechanism when turned on we experience general growth, stronger muscles, strength, energy, etc. When turned off we can revive our cells. The author tells how we can slow aging, possibly reversing it, by going back and forth between activating autophagy and mTOR, two very important cell processes. You can actually maintain your growth and switch to trashing out our bad cells, i.e. cancer, Alzheimers, diabetes, etc. We can live a much more healthy lifestyle, but most important we can extend our life span and possibly reverse our aging. The author also lays out a very practical method in turning the switch on or off. It’s something all of us can do ourselves.
13 people found this helpful
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Top reviews from other countries

P Manoj Kumar
5.0 out of 5 stars A great read
Reviewed in India on April 3, 2024
Verified Purchase
The book is written in a very simple & understandable English. Every health professional/nutritional advisors should read this book atleast once.
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Stan
5.0 out of 5 stars Must read
Reviewed in the United Kingdom on April 6, 2020
Verified Purchase
The more I read it the more I like it.
Obviously the main point of the book is the switch - mTOR and authopagy.
The book is big on intermittent fasting and keto diet.
Chapter 9 is extremely useful: it has practical recommendations about what to eat or not to eat to implement the ideas explained earlier.
I think it is the most impactful book I read in the last couple of years. It is going to make a difference in my life, as I am going to incorporate many of its ideas.
4 people found this helpful
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merry r.
5.0 out of 5 stars It is a good book
Reviewed in Japan on August 1, 2021
Verified Purchase
It is nice to know some information about aging from this book.
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SA Gamble
5.0 out of 5 stars This info plus no seed oils and you are set
Reviewed in Australia on July 13, 2020
Verified Purchase
He says,
"It pains me to watch someone order a plateful of fluffy buttermilk pancakes doused with lots of syrup and a side of bacon, followed by an order of cheesy pizza. Yes, I have witnessed this, and all I see is diabetes on a plate with heart disease for dessert. We deserve better."
So true, unfortunately.
Drop ALL seed oils and you are ahead of the race, the human race. Find Prof. Knobbe for seed oil info.
One person found this helpful
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Aviral
5.0 out of 5 stars Compulsory reading for people not wanting to die
Reviewed in India on August 30, 2020
Verified Purchase
Comprehensive body of work on how switching the body from anabolic to catabolic states, in the process activating from autophagy, can really do wonders for our health and longevity. Recommendations in the book are definitly worth implementing.
One person found this helpful
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