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DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences Paperback – January 1, 2001
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• A behind-the-scenes look at the cutting edge of psychedelic research.
• Provides a unique scientific explanation for the phenomenon of alien abduction experiences.
From 1990 to 1995 Dr. Rick Strassman conducted U.S. Government-approved and funded clinical research at the University of New Mexico in which he injected sixty volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an extraordinarily riveting inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical found in the psychedelic Amazon brew, ayahuasca, is also manufactured by the human brain. In Strassman's volunteers, it consistently produced near-death and mystical experiences. Many reported convincing encounters with intelligent nonhuman presences, aliens, angels, and spirits. Nearly all felt that the sessions were among the most profound experiences of their lives.
Strassman's research connects DMT with the pineal gland, considered by Hindus to be the site of the seventh chakra and by Rene Descartes to be the seat of the soul. DMT: The Spirit Molecule makes the bold case that DMT, naturally released by the pineal gland, facilitates the soul's movement in and out of the body and is an integral part of the birth and death experiences, as well as the highest states of meditation and even sexual transcendence. Strassman also believes that "alien abduction experiences" are brought on by accidental releases of DMT. If used wisely, DMT could trigger a period of remarkable progress in the scientific exploration of the most mystical regions of the human mind and soul.
- Print length358 pages
- LanguageEnglish
- PublisherPark Street Press
- Publication dateJanuary 1, 2001
- Dimensions6 x 1.1 x 9 inches
- ISBN-109780892819270
- ISBN-13978-0892819270
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From the Publisher

Chapter 12: Unseen Worlds
In this chapter, we begin following the spirit molecule into more unexpected territory. This terrain is not so easy to recognize or understand because the experiences are less clearly related to the thoughts, feelings, and bodies of our volunteers. Rather, they suggest freestanding, independent levels of existence about which we are at most only dimly aware. These reports challenge our world view, and they raise the emotional intensity of debate: “Is it a dream? A hallucination? Or is it real?” “Where are these places? Inside or out?” These are the some of the questions we’ll begin pondering as we review the following reports.
Volunteers have referred to these places already. Marsha journeyed to “the Taj Mahal,” and Cassandra was yanked into “the crazy circus sideshow” full of clowns and other beings. In this chapter, I will focus on this issue of “where.” Where does DMT take us by the hand and lead us to? This is a necessary part of mapping the spirit molecule’s territory.
Editorial Reviews
Review
"Rick Strassman's pioneering research work with DMT, a natural psychedelic drug used by Amazonian Indians, raises fascinating questions about the neurochemical basis of experience and the feasibility of conducting human research with mind-altering drugs in a university medical center. Truly adventurous reading!" ― Andrew Weil, M.D., author of Spontaneous Healing
"This book is essential reading for anyone with an interest in the mind, philosophy, the nature of reality, and spirituality." ― Karl Jansen, M.D., Ph.D.
"DMT: The Spirit Molecule points the way beyond the present impasse of the reigning 'drug abuse' paradigm." ― Jonathan Ott, author of The Age of Entheogens and Hallucinogenic Plants of North America
"The most extensive scientific study of the mental and perceptual effects of a psychedelic drug since the 1960s." ― Ralph Metzner, Ph.D., author of Ayahuasca: Consciousness and the Spirits of Nature
"Strassman's important research contributes to a growing awareness that we inhabit a multi-dimensional universe." ― John Mack, MD Professor of Psychiatry, Harvard Medical School, author of Abduction and Passport to t
"Strassman raises vital questions about the origin of spiritual experiences and the nature of consciousness." ― Larry Dossey MD, author of Reinventing Medicine, and Healing Words; Executive Editor, Alternative Th
"DMT: The Spirit Molecule is a fascinating journey into the research of psychedelics. . . . The questions and possible explanations about the endogenous presence of DMT that he raises not only enlarge the discussion about psychedelics but also expand our understanding of the nature of consciousness." ― Jule Klotter, Townsend Letter for Doctors & Patients - July, 2001
"This book will be of profound interest to . . . anyone with a deep interest in the study of consciousness, visionary states and/or psycho-pharmacology." ― J. P. Harpignies, Lapis
"Strassman's psychonauts regularly found themselves hurtled into alien laboratories, high-tech nurseries, and Day-Glo hieroglyphic hypercubes." ― Erik Davis, The Village Voice
"DMT: the Spirit Molecule is an enriching journey into one scientist's courageous attempt to solve a bit more of the brain/mind/spirit mystery at the center of human existence." ― Vicki Ecker, UFO Magazine, December-January 2002
"What you will find is a thoughtful, well-written report about another of life's mysteries." ― James Dekorne, Fortean Times, November 2001
"Strassman's research was an important step, one that will potentially illuminate the path for future researchers and volunteers alike, and this book is a great contribution to the ongoing dialogue surrounding psychedelics." ― Scotto, Trip, Fall 2001
"This is probably the most thorough book on the psychedelic, DMT--its history, chemistry, uses (legal and illegal), and its effects. This is a very compelling, thoughtful book, written by a scrupulous scientist with the soul of a meditator." ― The Book Reader, Spring/Summer 2002
"The account of the project is an excellent inside view of human drug studies, especially those with psychedelics." ― Paul Von Ward, The AHP Perspective, June/July 2002
"This book is a highly readable, intriguing, provocative description of Rick Strassman's theories and research concerning the effects of DMT." ― Alissa Hirshfeld-Flores, M.A., LMFT, The American Journal of Psychiatry, August 2002
"Rick Strassman's experimentation with the psychoactive substance DMT is taking up where Leary's 1950/60's LSD experiments stopped." ― Rev. Dr. S. D'Montford, New Dawn, Jan-Feb 2006
"[Strassman's] account, written more for the layman than the specialist, is ground-breaking, and raises the interesting question as to what is truly a psychedelic experience." ― Peter Fenwick, The Scientific and Medical Network, Summer 2007
"Near-death experiences. Alien abductions. Lucid dreams. Even gods and goddesses. Try DMT for an explanation and it all holds together. It's brain chemistry. It's neuropharmacology. It's quite possibly other realms. Whatever it is, it's the new frontier, a closer examination of consciousness, and it's very, very exciting!" ― betaphilings.com, Dec 2008
"[Strassman] is a gifted writer and makes scientific jargon easy to read. The book gives very interesting examples of what the volunteers envisioned and how they felt throughout the experiences. . . . It is important for us as a society to look at legal, controlled, and supervised experimentation with psychoactive drugs with open minds, and with eventual scientific benefit in mind." ― Levi Cox, FLC Law and Society Science & Metaphysics Blog, Feb 2009
"Fascinating stuff! If this kind of thing interests you then pick up this book today." ― Loretta Nall, blog by former Alabama Gubernatorial Candidate, June 2009
"In the end, I felt the most important element of the book was the contextualization of the questions most important in psychedelic research. Strassman keenly recognizes and extrapolates the areas that appear to be most vital in the further study and theory of psychedelics." ― The Psychedelic Press UK, Sept 2009
“Highly readable, intriguing, provocative. . . . [An] intellectually courageous book. . . . Will be of great use both to researchers and clinicians, as well as to laypeople.” ― American Journal of Psychiatry, 2002
“A dazzling journey through psychedelic drug experimentation and a tantalizing peek into a new model of how the brain and mind work. Strassman’s research points toward a physiological basis for spirit and its interaction with the human body; his data suggests that our brain chemistry allows us access to other realms of existence just when we need it most, and his story recounts both the dangers and promises of entering this brave new world.” ― Bruce Greyson, Editor, Journal of Near-Death Studies
“ . . . Having the mind and the courage . . . you’re such an important part of the psychedelic history of this country because what you did is you legitimized a very important thing.” ― Joe Rogan, from a conversation with Rick Strassman, M.D., regarding his contributions to psychedelic
Review
"Rick Strassman's pioneering research work with DMT, a natural psychedelic drug used by Amazonian Indians, raises fascinating questions about the neurochemical basis of experience and the feasibility of conducting human research with mind-altering drugs in a university medical center. Truly adventurous reading!" ― Andrew Weil, M.D., author of Spontaneous Healing
"This book is essential reading for anyone with an interest in the mind, philosophy, the nature of reality, and spirituality." ― Karl Jansen, M.D., Ph.D.
"DMT: The Spirit Molecule points the way beyond the present impasse of the reigning 'drug abuse' paradigm." ― Jonathan Ott, author of The Age of Entheogens and Hallucinogenic Plants of North America
"The most extensive scientific study of the mental and perceptual effects of a psychedelic drug since the 1960s." ― Ralph Metzner, Ph.D., author of Ayahuasca: Consciousness and the Spirits of Nature
"Strassman's important research contributes to a growing awareness that we inhabit a multi-dimensional universe." ― John Mack, MD Professor of Psychiatry, Harvard Medical School, author of Abduction and Passport to t
"Strassman raises vital questions about the origin of spiritual experiences and the nature of consciousness." ― Larry Dossey MD, author of Reinventing Medicine, and Healing Words; Executive Editor, Alternative Th
"DMT: The Spirit Molecule is a fascinating journey into the research of psychedelics. . . . The questions and possible explanations about the endogenous presence of DMT that he raises not only enlarge the discussion about psychedelics but also expand our understanding of the nature of consciousness." ― Jule Klotter, Townsend Letter for Doctors & Patients - July, 2001
"This book will be of profound interest to . . . anyone with a deep interest in the study of consciousness, visionary states and/or psycho-pharmacology." ― J. P. Harpignies, Lapis
"Strassman's psychonauts regularly found themselves hurtled into alien laboratories, high-tech nurseries, and Day-Glo hieroglyphic hypercubes." ― Erik Davis, The Village Voice
"DMT: the Spirit Molecule is an enriching journey into one scientist's courageous attempt to solve a bit more of the brain/mind/spirit mystery at the center of human existence." ― Vicki Ecker, UFO Magazine, December-January 2002
"What you will find is a thoughtful, well-written report about another of life's mysteries." ― James Dekorne, Fortean Times, November 2001
"Strassman's research was an important step, one that will potentially illuminate the path for future researchers and volunteers alike, and this book is a great contribution to the ongoing dialogue surrounding psychedelics." ― Scotto, Trip, Fall 2001
"This is probably the most thorough book on the psychedelic, DMT--its history, chemistry, uses (legal and illegal), and its effects. This is a very compelling, thoughtful book, written by a scrupulous scientist with the soul of a meditator." ― The Book Reader, Spring/Summer 2002
"The account of the project is an excellent inside view of human drug studies, especially those with psychedelics." ― Paul Von Ward, The AHP Perspective, June/July 2002
"This book is a highly readable, intriguing, provocative description of Rick Strassman's theories and research concerning the effects of DMT." ― Alissa Hirshfeld-Flores, M.A., LMFT, The American Journal of Psychiatry, August 2002
"Rick Strassman's experimentation with the psychoactive substance DMT is taking up where Leary's 1950/60's LSD experiments stopped." ― Rev. Dr. S. D'Montford, New Dawn, Jan-Feb 2006
"[Strassman's] account, written more for the layman than the specialist, is ground-breaking, and raises the interesting question as to what is truly a psychedelic experience." ― Peter Fenwick, The Scientific and Medical Network, Summer 2007
"Near-death experiences. Alien abductions. Lucid dreams. Even gods and goddesses. Try DMT for an explanation and it all holds together. It's brain chemistry. It's neuropharmacology. It's quite possibly other realms. Whatever it is, it's the new frontier, a closer examination of consciousness, and it's very, very exciting!" ― betaphilings.com, Dec 2008
"[Strassman] is a gifted writer and makes scientific jargon easy to read. The book gives very interesting examples of what the volunteers envisioned and how they felt throughout the experiences. . . . It is important for us as a society to look at legal, controlled, and supervised experimentation with psychoactive drugs with open minds, and with eventual scientific benefit in mind." ― Levi Cox, FLC Law and Society Science & Metaphysics Blog, Feb 2009
"Fascinating stuff! If this kind of thing interests you then pick up this book today." ― Loretta Nall, blog by former Alabama Gubernatorial Candidate, June 2009
"In the end, I felt the most important element of the book was the contextualization of the questions most important in psychedelic research. Strassman keenly recognizes and extrapolates the areas that appear to be most vital in the further study and theory of psychedelics." ― The Psychedelic Press UK, Sept 2009
“Highly readable, intriguing, provocative. . . . [An] intellectually courageous book. . . . Will be of great use both to researchers and clinicians, as well as to laypeople.” ― American Journal of Psychiatry, 2002
“A dazzling journey through psychedelic drug experimentation and a tantalizing peek into a new model of how the brain and mind work. Strassman’s research points toward a physiological basis for spirit and its interaction with the human body; his data suggests that our brain chemistry allows us access to other realms of existence just when we need it most, and his story recounts both the dangers and promises of entering this brave new world.” ― Bruce Greyson, Editor, Journal of Near-Death Studies
“ . . . Having the mind and the courage . . . you’re such an important part of the psychedelic history of this country because what you did is you legitimized a very important thing.” ― Joe Rogan, from a conversation with Rick Strassman, M.D., regarding his contributions to psychedelic
From the Back Cover
About the Author
Product details
- ASIN : 0892819278
- Publisher : Park Street Press; Later Printing edition (January 1, 2001)
- Language : English
- Paperback : 358 pages
- ISBN-10 : 9780892819270
- ISBN-13 : 978-0892819270
- Item Weight : 1.1 pounds
- Dimensions : 6 x 1.1 x 9 inches
- Best Sellers Rank: #38,665 in Books (See Top 100 in Books)
- Customer Reviews:
About the author

Rick Strassman, M.D., author of "DMT: The Spirit Molecule," and co-author of "Inner Paths to Outer Space," lives in Gallup, New Mexico, and is Clinical Associate Professor of Psychiatry at the University of New Mexico School of Medicine. A native of Los Angeles, his undergraduate studies occurred at Pomona College and Stanford University, medical training at Albert Einstein College of Medicine of Yeshiva University, psychiatry residency at UC Davis, and psychopharmacology fellowship at UC San Diego. He performed the first new human research with hallucinogenic drugs in the U.S. in a generation. In "DMT and The Soul of Prophecy" (Inner Traditions), and has developed a new top-down model of religious/prophetic experience, "theoneurology." This new model provides a theistic complement to that of the reigning materialistic bottom-up neurotheology. His website is www.rickstrassman.com
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Customers find the book extremely readable and consider it an instant classic, providing great insight into the psychedelic experience. They appreciate the profound understanding of the spirit molecule, with one customer noting its good mix of spirituality and science. The storytelling receives mixed reactions - while some find it spellbinding, others note it includes unnecessary details.
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Customers find the book extremely readable and an instant classic, describing it as a mind-opening read.
"...Or maybe it is, because it can help balance that out with a healthy dose of realism...." Read more
"Love the book" Read more
"...Rich Strassman's writing style makes this book extremely readable, and the DMT subjects' reports and anecdotal stories make the book difficult to..." Read more
"...Just enough detail to make the subject matter understandable. Well Done!" Read more
Customers find the book insightful, particularly appreciating its research-based approach and thought-provoking content, with one customer noting its good mix of spirituality and science.
"...I found the section engaging and also important, because when Strassman published it in 2001, he was providing a road map for other researchers to..." Read more
"...psychedelics are an absolute miracle, and they must be given the respect they deserve. LONG LIVE THE PINEAL GLAND!" Read more
"...I hope it can do some good. The subjects’ stories are great. Particularly was interested in how many of them saw non-human intelligences (ET’s.)" Read more
"Informative. Just enough detail to make the subject matter understandable. Well Done!" Read more
Customers appreciate the book's exploration of the spirit molecule, describing it as an amazing compound with profound insights into its nature.
"...perspective offers another roadmap for how to look at these amazing compounds and maintain a stance of neutrality and curiosity, rather than..." Read more
"...It is simply a distillate of this natural substance, which is produced by the human pineal gland...." Read more
"...been allowed to research these extremely interesting, extremely promising molecules, although psychedelics were THE most exciting, most promising..." Read more
"This and Light on dmt are the 2 best books I have read about this amazing molecule so far. I highly reccomend this duo if you have interest in DMT." Read more
Customers appreciate the book's integrity, noting its good physical condition, with one customer highlighting its strong case.
"...to hear their wild testimonies, and Strassman does an excellent job maintaining his integrity and his scientific stance as a researcher...." Read more
"...The book arrived in good physical condition." Read more
"...One has to admire his integrity, perseverance, and dedication to the scientific exploration of human consciousness...." Read more
"...model, but I also feel that Strassman should be commended for his integrity, honesty, thoroughness and willingness to consider realms that were..." Read more
Customers have mixed opinions about the storytelling in the book, with some finding it great and absolutely spellbinding, while others note that it includes many unnecessary details.
"...It is remarkable to hear their wild testimonies, and Strassman does an excellent job maintaining his integrity and his scientific stance as a..." Read more
"...The second problem, is the overly medical descriptions. Yes I realize he is a Doctor. It felt like reading a scientific journal at times...." Read more
"...The inbetween of the memorable moments is filled with great storytelling of how this book came to be or more science and history, which is still..." Read more
"...The book is bloated with unnecessary content, however...." Read more
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Incredible book
Top reviews from the United States
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- Reviewed in the United States on July 8, 2022DMT: The Spirit Molecule is a remarkable book, made all the more remarkable that it was first published in 2001, well before this current "psychedelic renaissance" reached the popularity it currently has. In that popularity's excess focus on Johns Hopkins and MAPS, Strassman does not get the credit he deserves. When he conducted the multi-year study this book elaborates, no one else in the entire country was conducting above-ground psychedelic research in direct relationship with an academic institution and the Federal government. That had not happened since around 1970. Strassman's tenacity, commitment, and willingness to find new pathways opened the door, and without his work, that door could still be closed.
And then there's the research itself. The sections about the research subjects' subjective experiences with DMT were among the most fascinating chapters I've ever read. It is remarkable to hear their wild testimonies, and Strassman does an excellent job maintaining his integrity and his scientific stance as a researcher. A gripping inner conflict emerges -- does he reduce the subjects' experiences to a scientific explanation, or does he take a bold leap into listening to their reports of "beings" and "other realms" as if they are real, as the subjects so adamantly expressed?
Some negative reviews claim that Strassman spends too much time explaining all that he had to go through to get the research going. I have a very different perspective on this. I found the section engaging and also important, because when Strassman published it in 2001, he was providing a road map for other researchers to follow in his tracks and re-establish psychedelic research in U.S. universities. As an important piece of psychedelic history, it's so valuable to have his detailed account for reference, and the sheer amount of challenges he overcame serves as a good lesson about the importance of follow-through on a vision, even in the face of seemingly insurmountable odds.
Lastly, what makes this book so impactful is that Strassman is a grounded realist. He does not get swept up into overly-blissful psychedelic enthusiasm and make extreme claims. He does not cut out information gained from the study that show the real dangers of psychedelics. In a time when over-glorification of psychedelics consistently misguides a curious and suffering public, Strassman's balanced perspective offers another roadmap for how to look at these amazing compounds and maintain a stance of neutrality and curiosity, rather than zealotous religious fervor. If you are looking for a book to confirm your already-existing beliefs that psychedelics are a panacea or magic pill, this is not the book for you. Or maybe it is, because it can help balance that out with a healthy dose of realism.
I hope that people continue to read and reference this book, and I hope that more people acknowledge it as the groundbreaking work that it is. We are lucky to have Rick Strassman.
- Reviewed in the United States on March 9, 2025Love the book
- Reviewed in the United States on August 14, 2017...as Dr. Strassman arrives at some very different conclusions from the ideas he expresses before and during the trial process...and i whole-heartedly agree with his arrival at the idea that the DMT experience may not be something that we can easily describe or quantify with human communication.
MY conclusions: 1) DMT is not a toy, and 2) there may be a reason that the body strictly controls the production of DMT...as it may be a substance that is produced only when we are "in extremis."
my disclaimers:
1) although i am not a scientologist, i do not subscribe to the fields of psychiatry & psychology...and the ever-expanding Diagnostic and Statistical Manual of Mental Disorders (DSM). these fields essentially dictate: if you don't see and react to the physical world in the same way i do, then you are crazy...and i can lock you up in a mental facility.
the myriad variations of personality & consciousness of human beings are not quantifiable or completely describable, except on an individual basis...and perhaps not even then.
[edit 15aug2017] i mention my opinion on the "psych" field only because Strassman seemed to feel it necessary to put the experiences of the research subjects into the 'correct' description check-boxes of human behavior required by the DSM and therapeutic technique. there were a few times when i read what Strassman quoted the patient as saying about a DMT experience, and when i read his summation of that experience, it didn't seem to be AT ALL what the patient described...sometimes in the patient's intent and sometimes in the patient's description of an experience.
it isn't until the Conclusion section that Strassman begins to realize that he might have done better to simply provide a source of mostly silent comfort to the patient, while recording the patient's report of the experience...WITHOUT ATTEMPTING TO LEAD THE PATIENT INTO THE REQUIRED SOCIETAL EXPLANATIONS.
the other truly disturbing example of this behavior is the "recovered memory" industry, which seems to push, push, push to get the societally desired response from the patient...in order to reinforce the societal backstory currently in play.
in the 1980s, it was determined by the psych industry that we were all co-dependent, which is what i said to my Ph.D psychologist sister after reading an article she gave me. "Well, B___, this seems like a mandate for job creation for the psych industry...but not much more than that," and we haven't really communicated much since then.
to sum up: in my opinion, the psych industry is determined to convince the world that they have all the answers to all the world's mental and behavior problems...but DMT transcends all those answers because it is an ineffable experience, and, therefore, incapable of being expressed to others in any meaningful way. the psych industry doesn't like what it can't categorize and/or quantize.
2) i do not believe that the brain is the electro-chemical producer of "consciousness" or "soul." i believe that consciousness is the very fabric of the universe..and our souls are a part of that consciousness.
as one of my philosophy professors put it (in the 1980s): God (or, the universe) is Thinking...thinking about thinking. (thank you, Robert Helbling.)
i believe that the brain IS the administration building for the body...in other words, a set of civil servants responding to the requests for materials from individual cells or groups of cells in the body.
3) i believe that the brain functions as a FILTER to keep the rest of the universe OUT of our current existence in this dimension of existence...ONLY TO KEEP US FOCUSED ON THE TASK(S) AT HAND IN THE HERE AND NOW.
by taking DMT, we are asking to take a peek at things that we have great difficulty understanding in our present state. if we take DMT (or shrooms) without the right intent, then we are wasting our time and money...and confusing & scaring ourselves with visions of things that are beyond our ability to comprehend at the moment.
psychedelics are an absolute miracle, and they must be given the respect they deserve.
LONG LIVE THE PINEAL GLAND!
- Reviewed in the United States on April 12, 2025I’m not a fan of chemical enlightenment but it’s good to see how DMT affects people. I hope it can do some good. The subjects’ stories are great. Particularly was interested in how many of them saw non-human intelligences (ET’s.)
Top reviews from other countries
- Adrian CharecReviewed in Italy on February 14, 2019
5.0 out of 5 stars Excellent
Great
- Angie S.Reviewed in Australia on November 10, 2020
5.0 out of 5 stars Mind Blowing
It opened my mind into many related questions of humanity. There are not certain answers but it gave me certain questions , new ideas and better understanding of how different are drugs and how we classified them as one when they are all different. A new pathway to look forward better psychological support. I won’t say how good or bad the book was, It is what this scientific has to offer and I’m glad he dedicated his life for future generations to keep understanding our own evolution , our own propose , our position in the universe.
-
LeonardoReviewed in Brazil on July 7, 2022
5.0 out of 5 stars Muito bom!
Bem escrito, temas divididos, conteúdo esclarecedor. Pode comprar!
- Bogdan VieruReviewed in Germany on July 20, 2024
5.0 out of 5 stars Simply wonderful
Amazing book, great level of detail regarding the studies done and the experience of the participants. Also lent it to some friends and it helped them change their perspective of the current social paradigm that all illegal drugs are bad and deadly.
- Shane P.Reviewed in Canada on July 7, 2024
5.0 out of 5 stars Interesting read
For those interested in psychedelics and their effects on the human mind, you should find this to be worth your while. I found this to be a very enjoyable read.