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Eric J. Topol
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The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care 1st Edition, Kindle Edition

by Eric Topol (Author) Format: Kindle Edition
4.4 4.4 out of 5 stars 416 ratings
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How genomics, big data, and digital technology are revolutionizing every aspect of medicine, from physical exams to drug prescriptions to organ transplants

Mobile technology has transformed our lives, and personal genomics is revolutionizing biology. But despite the availability of technologies that can provide wireless, personalized health care at lower cost, the medical community has resisted change. In The Creative Destruction of Medicine, Eric Topol-one of the nation's top physicians-calls for consumer activism to demand innovation and the democratization of medical care. The Creative Destruction of Medicine is the definitive account of the coming disruption of medicine, written by the field's leading voice.
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  1. ISBN-13
    978-0465025503
  2. Edition
    1st
  3. Sticky notes
    On Kindle Scribe
  4. Publisher
    Basic Books
  5. Publication date
    December 2, 2011
  6. Language
    English
  7. File size
    2484 KB
  8. See all details
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From the Publisher

Topol Topol
Deep Medicine The Patient Will See You Now
Customer Reviews
4.6 out of 5 stars
816
4.4 out of 5 stars
558
Price $17.99 $15.58
Explore the Works of Eric Topol Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved. The essential guide by one of America’s leading doctors to how digital technology enables all of us to take charge of our health.

Editorial Reviews

Review

"Dr. Eric Topol is an extraordinary doctor. He's started a leading medical school, identified the first genes to underlie development of heart disease, led major medical centers, and been a pioneer of wireless medicine. But he is also a remarkable communicator-one of the few top-flight scientists in medicine to be able to genuinely connect with the public. He was, for example, the first physician researcher to question the safety of Vioxx-and unlike most who raise safety questions, actually succeed in bringing the concerns to public attention. I have known and admired Dr. Topol for a long time. I recommend him highly."―Atul Gawande, M.D., author of The Checklist Manifesto

"It may sound like hyperbole, but it's true: Medicine is undergoing its biggest revolution since the invention of the germ theory. As Eric Topol writes, thirty years ago, 'digital medicine' referred to rectal examinations. Dr. Topol is both a leader of and perfect guide to this brave new health world. His book should be prescribed for doctors and patients alike."―A. J. Jacobs, author of My Life as an Experiment and The Year of Living Biblically

"This is the one book to read for a complete and clear view of our medical future, as enabled by the convergence of digital, mobile, genomic, and life science breakthroughs. Dr. Topol explains how iPhones, cloud computing, gene sequencing, wireless sensors, modernized clinical trials, internet connectivity, advanced diagnostics, targeted therapies and other science will enable the individualization of medicine -- and force overdue radical change in how medicine is delivered, regulated, and reimbursed. This book should be read by patients, doctors, scientists, entrepreneurs, insurers, regulators, digital engineers -- anyone who wants better health, lower costs, and participation in this revolution."―Brook Byers, Partner, Kleiner Perkins Caufield & Byers

"Eric Topol is that rare physician willing to challenge the orthodoxies of his guild. He recognizes that in the U.S., health care business-as-usual is unsustainable. But he does not despair. He bears witness to the rise of Homo digitus and the promise it holds to upend the inefficiencies and dysfunction so entrenched in clinical medicine. The Creative Destruction of Medicine is a timely tour de force. It is a necessary heresy."

Clayton M. Christensen, Robert and Jane Cizik Professor of Business Administration, Harvard Business School, and author of The Innovator's Dilemma

"Eric Topol gives us an eye-opening look at what's possible in healthcare if people can mobilize to charge the status quo. The Creative Destruction of Medicine is simply remarkable."―Misha Angrist, assistant professor, Duke Institute for Genome Sciences & Policy, and author of Here is a Human Being

"Eric Topol outlines the creative destruction of medicine that must be led by informed consumers. Smart patients will push the many stakeholders in health to accelerate change as medicine adapts to a new world of information and technology."―Mehmet Oz, M.D., professor and Vice-Chair of Surgery, NY Presbyterian/Columbia University

"Eric Topol has been a longtime innovator in healthcare. In The Creative Destruction of Medicine, he cites the big waves of innovation that will save healthcare for the future. Real healthcare reform has not yet begun, but it will. The Creative Destruction of Medicine lays out the path."―Jeffrey Immelt, Chairman and CEO of General Electric

"Eric Topol provides an excellent and pragmatic view of the U.S. healthcare system from a patient's perspective. He then offers, through numerous examples, an exciting vision for the future...when technology can be used to dramatically improve the quality of care and reduce cost at the same time. The Creative Destruction of Medicine is a highly informative and enjoyable book, which truly triggers the reader's imagination as to what is possible"―Omar Ishrak, Chairman and CEO of Medtronic

"Eric Topol has written an extraordinarily important book at just the right moment. Drawing upon a unique and impressive array of convergent expertise in medical research, clinical medicine, consumer and health technological advancements, and health policy, Dr. Topol opens the door for an essential discussion of old challenges viewed through an innovative lens. In the context of increasingly unaffordable health care costs, suboptimal quality of care delivery, a tsunami of preventable chronic illness, and new accountabilities for consumer's health choices and behaviors, this book helps all of us to think about solutions in new and exciting ways!"―Reed Tuckson, M.D., Executive Vice President and Chief of Medical Affairs, UnitedHealth Group

"Health care is poised to be revolutionized by two forces -- technology and consumerism -- and Dr. Eric Topol explains why. One-size-fits-all medicine will soon be overtaken by highly personalized, customized solutions that are enabled by breakthroughs in genomics and mobile devices and propelled by empowered consumers looking to live longer, healthier lives. Fasten your seat belts and get ready for the ride -- and learn what steps you can take to begin to take control of your health."―Steve Case, co-founder, AOL, and founder of Revolution LLC

"Eric Topol is uniquely positioned to write such a timely and important book. He leads two institutions -- one in genomics and one in wireless health -- that will each play a huge role in transforming medicine in the twenty-first century. From this vantage point, he can see unifying themes that will underlie the coming revolution in population and personal health, and he communicates his vision with vibrant energy. Everyone will want to read this book."―James Fowler, professor of medical genetics and political science, UC San Diego, and author of Connected

"What happens when the super-convergence of smart phones further combines with million-fold lower-cost genomics and diverse wearable sensors? The riveting answer leads compellingly to a call to activism -- not only for medical care providers, but all patients and everyone looking for the next 'disruptive' economic revolution. This future is closer than most of us would have imagined before seeing it laid out so clearly. A must-read."―George Church, professor of genetics, Harvard Medical School

"Our sequencing of the human genome eleven years ago was the beginning of the individualized medicine revolution, a revolution that cannot happen without digitized personal phenotype information. Eric Topol provides a path forward using your digitized genome, remote sensing devices and social networking to place the educated at the center of medicine."―J. Craig Venter, Chairman and President, J. Craig Venter Institute

About the Author

Eric Topol, MD, is a world-renowned cardiologist, Executive Vice-President of Scripps Research, founder of a new medical school and one of the top ten most cited medical researchers. The author of The Patient Will See You Now and The Creative Destruction of Medicine, he lives in La Jolla, CA.

Product details

  • ASIN ‏ : ‎ B006NV93U8
  • Publisher ‏ : ‎ Basic Books; 1st edition (December 2, 2011)
  • Publication date ‏ : ‎ December 2, 2011
  • Language ‏ : ‎ English
  • File size ‏ : ‎ 2484 KB
  • Text-to-Speech ‏ : ‎ Enabled
  • Screen Reader ‏ : ‎ Supported
  • Enhanced typesetting ‏ : ‎ Enabled
  • X-Ray ‏ : ‎ Not Enabled
  • Word Wise ‏ : ‎ Not Enabled
  • Sticky notes ‏ : ‎ On Kindle Scribe
  • Print length ‏ : ‎ 322 pages
  • Customer Reviews:
    4.4 4.4 out of 5 stars 416 ratings

About the author

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Eric J. Topol

Eric J. Topol

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Dr. Topol, an Elsevier Author, received his Bachelor of Arts with highest distinction from the University of Virginia in 1975, his doctor of medicine with honor from the University of Rochester School of Medicine in 1979, and completed internal medicine residency at University of California, San Francisco, and cardiology fellowship at Johns Hopkins University.

For more information, visit http://elsevierauthors.com/erictopol/

Customer reviews

4.4 out of 5 stars
4.4 out of 5
416 global ratings

Top reviews from the United States

Kathleen Scarbrough
5.0 out of 5 stars Health Care's Schumpeter Moment
Reviewed in the United States on March 18, 2012
Verified Purchase
Dr. Eric Topol's book is an excellent review of what the promise of technology holds for the US Healthcare system. His background as a geneticist and a cardiologist as well as a highly regarded research scientist informs this book with the promise of the future, and it is the near future at that. Not something decades away. The advent of the empowered patient (by technology as close as their cell phone) extends the opportunity and methodology for significant reductions in the cost of health care for us all---without a reduction in quality. For instance, cell phones with a "lab on a chip" enabling individuals to substantially reduce the cost and compliance of monitoring one's blood work for glucose, cholesterol, etc. while empowering the patient to be more aware and in control.

His review of genetics was a little dense, but as readers we must all bear in mind how difficult it is to condense such a complex subject into a chapter of one book providing enough information for the lay person to become excited about the possibilities in front of us without speaking totally over our heads. The promise of pharmacogenomics is here today. Enabling an oncologist to test a cancer tumor for genetic markers that indicate which of several chemotherapy drugs would be most efficacious for a particular patient. The "wrinkle" in the system is that insurance company awareness and subsequent payments are running behind the speeding train of "Star Trek" medicine. I do believe we will as a society work this out.

As a health care professional, I highly recommend this book for nurses, physicians, administrators as well as interested lay people. There are so many cost pressures coming with health care reform, it is easy to get caught up in thinking that quality of care is doomed to decline. This book opened my eyes to the possibilities in front of us today and many hopes in front of us within the next 5 years. It truly lifted my spirits to read it.

Thank you Dr. Topol.
43 people found this helpful
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Bobbie Hennessy
4.0 out of 5 stars The physician practice of the future!
Reviewed in the United States on April 22, 2013
Verified Purchase
I haven't finished reading the book yet, but for me I am enjoying it very much. I used to run hospitals and physician practices for more than 30 years so this information is very intriguing to me personally. Especially in light of Obamacare coming into effect very soon. People will be shocked to know what they truly got!

I would love to design such a practice and am contemplating contacting Dr. Topol as I believe it can be done and safe consumers lots of money and much UNNECESSARY time in the physician office. Our experience and relationship with our physicians is paramount to ongoing good health and WE must take part in living a healthy lifestyle.

If you are not in this field you may not appreicate all the intimate details and he did not do much to make the book easy to read or an attractive coffee table book it is NOT! But then, he is a doctor and not an artist. But, if you want to look into what medicine can do, you will enjoy the information as I am finding it fascinating.

Bobbie in Raleigh
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Anne Mills
5.0 out of 5 stars Key Reading for Those Who Deal With Medicine, Patients Especially
Reviewed in the United States on December 4, 2012
Verified Purchase
This book merits five stars for content. I'd have shaved one away, because this was NOT an easy book to read. The topic, however, is so important that we'll leave a full array. In any event, if your life intersects with medicine in a major way, read it.

Dr. Topol is an eminent cardiologist, geneticist, and medical researcher. Here, he argues that the practice of medicine is on the brink of massive structural change. The title attributes this to the digital revolution, but the book is at least as much about the impact of the science of genetics. The combination of these two will produce a medical approach far more closely targetted to the individual, far more precise, and -- ulimately -- far cheaper.

A great deal of what Dr. Topol says is very informative and very convincing. Some of it is so "gee whiz" as to be offputting, and some of it sounds like science fiction. Much of what sounds like science fiction, however, is already in development. And some of it is already moving into current practice -- by patients as well as by doctors.

This is very important reading for those who have heavy contact with the healthcare system. One of Dr. Topol's key points is that as information becomes much more readily available, patients will have to take on more responsibility for their own care -- no one doctor can make all the right decisions in every area, and no one knows a patient like the patient him or herself. There is a lot in this book that's essential knowledge for those with serious conditions (or those who are helping those with serious conditions). The rather horrifying chapter on medical errors stands out, but there is much, much more.

My only problem with the book is that I found it a tough read. That's not so much because it was over-technical. The one instance in which that may be true is the section on the role of genomics in medicine, but that is a hard thing to explain, and not part of the general medical knowledge base -- Dr. Topol notes that at the last report, only 2 out of 150 U.S. medical schools had "more than a brief, cursory curriculum" devoted to genomics beyond simple Mendelian traits. My problem was with the overall approach, which is to throw lots and lots and LOTS of information at the reader, without enough explanation or linking together.

Stylistic issues, however, should not deter readers: there's so much very important stuff in this book that it's worth a bit of a slog. Moreover, the readability problem may be with this (elderly) reviewer. Two generally favorable reviews didn't seem to find it a problem. See the Wall Street Journal review at [...]at [...]

Anyway, read it.
7 people found this helpful
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Top reviews from other countries

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Flávia
5.0 out of 5 stars Medicina:o que conhecemos está mudando. É rápido!
Reviewed in Brazil on August 21, 2017
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Livro indispensável para se situar e participar da mudança em curso. O livro traz muitas referências interessantes, o que faz estender sua leitura para muito além
One person found this helpful
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Yathish chandra
5.0 out of 5 stars Excellent
Reviewed in India on March 5, 2019
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Excellent
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Guido G.
5.0 out of 5 stars interessante
Reviewed in Italy on May 27, 2016
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un libro che ispira e anticipa dei trend che già oggi vediamo all'orizzonte, la medicina basata sul genoma, i pazienti connessi etc etc a me è piaciuto ad alcuni è sembrato scontato....dipende dal lettore e dalle sue aspettative e livello di conoscenza
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Glen Tolhurst
5.0 out of 5 stars TOPOL'S BOOK
Reviewed in Canada on May 12, 2014
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Excellent book that is a good read.
Starts off with lots of technical innovations but loses pace mid book.
Still interesting.
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snowvirus
5.0 out of 5 stars Groundbreaking!
Reviewed in Germany on October 1, 2013
Verified Purchase
As an MD I agree with Dr. Topol in most points: medicine needs to open up to new concepts of acquiring, processing, and dispersing information. Individualized, rather than population-based, medicine is the key to a safer and more efficient treatment.
A must-read for any doctor (and patient!) in the 21st century!
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