"It is an essential read for all occupational health practitioners in training and those participating in a systematic evidence review or the development of evidence-based practice guidelines." (Occupational Medicine, 11 December 2011)

"To some extent forget the "evidence-based medicine" tag; while some chapters are specific to medical research, many others have generic value for any field of research ... This is a useful supplement that will aid anyone new to the assessment game." (Online Information Review, 2011)

"In summary, this book presents with not only some interesting research material itself, but also provides valuable insight into the reading and interpretation of technical and research papers. As a laboratory professional, this text can help to move you from merely a reader to papers to a user of papers. This step can take you to a new level in your laboratory career. Definitely worth the read or at least the scan." (Advance for Medical Laboratory Professionals, 10 October 2011)

"It will be a great tool for students, teachers and others in the world of academia, as well as patients who want to find out more about their condition, and who are new to reading journal papers and other documents which consider evidence-based medicine . . . It is good to see this book in its 4th edition and this reviewer hopes it continues to be revised as it really does provide a basic one-stop shop if you are new to evidence-based medicine." (The Encephalitis Society, 2011)

"Writing for health students and professionals, and anyone wanting to assess the validity of articles, Greenhalgh (primary health care, Queen Mary, U. of London, UK) explains the principles of evidencebased medicine and how to critically evaluate clinical research papers. She details how to evaluate different types of papers, such as papers on drug treatments and simple interventions, diagnostic and screening tests, those that summarize other papers, guidelines, economic analyses, and qualitative research." (Book News, September 2010)Trisha Greenhalgh is a doctor, not a statistician, and she is writing about a topic, Evidence-Based Medicine (EBM) that might appear at first to be irrelevant to us statisticians. It is not irrelevant. Any statistician who works extensively with health care professionals should embrace the EBM movement." (Journal of Biopharmaceutical Statistics , 2011)

"The book does show you how to put your brain into thinking gear and not just absorb information without thinking about it making this an excellent book. If I can react so strongly in this review, then it has to be worth something." (SFCrowsnest.co.uk, July 2010)

The author's descriptions of clinical research papers and how to critically appraise them are so simply presented as to be understandable by readers at all levels, from student to specialist. Chapters on searching the literature and implementing the evidence provide guidance on using evidence-based medicine in clinical practice.

This fourth edition retains the winning style, and takes in the recent developments and shifts of emphasis in evidence-based medicine and now includes:

• Thoroughly revised and updated chapters on searching, qualitative research, systematic review, and implementing evidence-based practice
• 2 new chapters on quality improvement and the emerging field of complex interventions

  This new edition will be welcomed by those who teach and those needing to learn the basics of evidence-based medicine.Praise for previous editions

  "One of the greatest aspects of this book is the section relating to searching the literature and whilst we may think we may all practise this on a fairly regular basis under the assumption that we do a pretty decent job of it, this section holds the key to excelling."
  From a review in Urology News

  "This clear and concise book provides an excellent starting point for those interested in finding their way through the medical literature."
  From a review in Palliative Medicine